Invention Grant
- Patent Title: Crystal form of orexin receptor antagonist compound, and preparation method and application thereof
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Application No.: US15752290Application Date: 2016-08-11
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Publication No.: US10668066B2Publication Date: 2020-06-02
- Inventor: Songliang Wu , Zhi Luo , Yuan Chen , Yuhe Wang , Dakun Qin , Xiaolin Li , Zheng Wang , Weidong Li , Haiying He
- Applicant: Shanghai Haiyan Pharmaceutical Technology Co., Ltd. , Yangtze River Pharmaceutical Group Co., Ltd.
- Applicant Address: CN Shanghai CN Taizhou, Jiangsu
- Assignee: Shanghai Haiyan Pharmaceutical Technology Co., Ltd.,Yangtze River Pharmaceutical Group Co., Ltd.
- Current Assignee: Shanghai Haiyan Pharmaceutical Technology Co., Ltd.,Yangtze River Pharmaceutical Group Co., Ltd.
- Current Assignee Address: CN Shanghai CN Taizhou, Jiangsu
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Agent Lars H. Genieser; Ming He
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7f1b7dd7
- International Application: PCT/CN2016/094558 WO 20160811
- International Announcement: WO2017/028732 WO 20170223
- Main IPC: C07D451/02
- IPC: C07D451/02 ; A61K31/506 ; A61K31/46 ; A61P25/34 ; A61P25/20 ; A61P25/22 ; A61P11/08
Abstract:
Disclosed are a preparation method of an orexin receptor antagonist compound 5-3, Crystalline forms I-IV of an orexin receptor antagonist compound 5-3 are provided. Also provided are processes of the preparing the orexin receptor antagonist compound 5-3 and its crystalline forms, as well as methods of using the crystalline forms I-IV for treating an orexin-related disease.
Public/Granted literature
- US20180235965A1 CRYSTAL FORM OF OREXIN RECEPTOR ANTAGONIST COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF Public/Granted day:2018-08-23
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