Invention Grant
- Patent Title: Pyridine sulfonamides
-
Application No.: US16319783Application Date: 2017-07-20
-
Publication No.: US10668067B2Publication Date: 2020-06-02
- Inventor: Matthew Weiss , John R. Butler , Benjamin Charles Milgram , Gwenaella Rescourio , Alessandro Boezio , Brian Andrew Sparling , Daniel La
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- International Application: PCT/US2017/043173 WO 20170720
- International Announcement: WO2018/017896 WO 20180125
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/4439 ; A61P25/00 ; C07D213/75 ; C07D401/12 ; C07D413/12 ; C07D417/12

Abstract:
The present invention provides compounds of Formula (I), as defined in the specification, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders, cough, or itch. Also provided are pharmaceutical compositions containing compounds of the present invention.
Public/Granted literature
- US20190167682A1 PYRIDINE SULFONAMIDES Public/Granted day:2019-06-06
Information query
IPC分类: