Invention Grant
- Patent Title: Nanoparticle complexes of albumin, paclitaxel, and panitumumab for treatment of cancer
-
Application No.: US15187672Application Date: 2016-06-20
-
Publication No.: US10668151B2Publication Date: 2020-06-02
- Inventor: Svetomir N. Markovic , Wendy K. Nevala
- Applicant: Mayo Foundation for Medical Education and Research
- Applicant Address: US MN Rochester
- Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- Current Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- Current Assignee Address: US MN Rochester
- Agency: Myers Bigel, P.A.
- Main IPC: A61K39/44
- IPC: A61K39/44 ; A61K39/395 ; C07K16/32 ; A61K33/24 ; A61K31/555 ; A61K9/51 ; A61K47/64 ; A61K47/68 ; A61K47/69 ; A61K9/00 ; A61K41/00 ; A61K45/06 ; C07K16/22 ; C07K16/28 ; A61K31/337 ; C07K16/30 ; A61K31/282 ; A61K9/14 ; A61K39/00 ; B82Y5/00
Abstract:
This invention relates to antibody-albumin nanoparticle complexes comprising albumin, an antibody with binding specificity for a cancer antigen (e.g. panitumumab), and paclitaxel, wherein the nanoparticle complex has been pre-formed in vitro such that the nanoparticle complex has antigen-binding specificity (e.g. EGFR binding specificity), for the purpose of providing cancer (e.g. EGFR-related cancer) treatments in a subject in need thereof.
Public/Granted literature
- US20160324964A1 CANCER TREATMENTS Public/Granted day:2016-11-10
Information query
