Invention Grant
- Patent Title: Solid supports for use in solid-phase peptide synthesis, kits, and related methods
-
Application No.: US16067727Application Date: 2017-02-03
-
Publication No.: US10669306B2Publication Date: 2020-06-02
- Inventor: Champak Chatterjee , Patrick M. Shelton , Caroline E. Weller
- Applicant: UNIVERSITY OF WASHINGTON
- Applicant Address: US WA Seattle
- Assignee: University of Washington
- Current Assignee: University of Washington
- Current Assignee Address: US WA Seattle
- Agency: Christensen O'Connor Johnson Kindness PLLC
- International Application: PCT/US2017/016455 WO 20170203
- International Announcement: WO2017/136690 WO 20170810
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K1/02 ; C07K1/04 ; C40B50/18 ; C07C323/10 ; C07K1/107 ; C07K17/08

Abstract:
Solid supports for use in solid-phase peptide synthesis (SPPS) are provided. The solid supports may include a resin and a protected linker coupled to the resin. The linker may be an N-mercaptoethoxyglycine, an N-mercaptopropoxyglycine, an N-mercaptobutoxyglycine, and/or another suitable linker. Kits for use in SPPS are also provided. The kits may include a solid support, a solution including a thiol or a selenol, one or more pluralities of protected amino acids, and/or a wash buffer. Methods of SPPS are also provided. The methods may include providing a solid support including a resin coupled to a protected linker.
Public/Granted literature
- US20190010186A1 SOLID SUPPORTS FOR USE IN SOLID-PHASE PEPTIDE SYNTHESIS, KITS, AND RELATED METHODS Public/Granted day:2019-01-10
Information query