Invention Grant
- Patent Title: Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an antibody to IL-4 receptor
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Application No.: US15842865Application Date: 2017-12-14
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Publication No.: US10669341B2Publication Date: 2020-06-02
- Inventor: Neil Stahl , Jamie M. Orengo , Andrew J. Murphy , Namita Gandhi , Neil Graham
- Applicant: Regeneron Pharmaceuticals, Inc.
- Agency: Merchant & Gould P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K45/06 ; A61P37/02 ; A61K39/00

Abstract:
The present invention provides methods for treating, preventing or reducing the severity of allergic reactions. The present invention also provides methods for enhancing the efficacy and/or safety of an allergen-specific immunotherapy (SIT) regimen. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4Rα) antagonist such as an anti-IL-4Rα antibody.
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