Invention Grant
- Patent Title: Means and methods for the generation of mammalian producer cells for the production of recombinant proteins
-
Application No.: US14910267Application Date: 2014-07-30
-
Publication No.: US10669541B2Publication Date: 2020-06-02
- Inventor: Marc Feary , James Rance , Robert Young , Elizabeth C. Sayer , Christopher M. Smales
- Applicant: LONZA BIOLOGICS PLC
- Applicant Address: GB Slough
- Assignee: LONZA BIOLOGICS PLC.
- Current Assignee: LONZA BIOLOGICS PLC.
- Current Assignee Address: GB Slough
- Agency: Lucas & Mercanti, LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@76bbbc6e
- International Application: PCT/EP2014/066352 WO 20140730
- International Announcement: WO2015/018703 WO 20150212
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12P21/00 ; C12N15/11 ; C07K16/00
Abstract:
Methods for generating mammalian cells characterized by an increased concentration of at least one of miR-15, miR-16, and miR-34 for producing proteins at an industrial scale are provided. Methods for using the mammalian cells, in particular for the production of proteins of interest, are also provided.
Public/Granted literature
Information query
IPC分类:
