Device and method for analysis of tyres are presented. The device includes a support frame, a flange, and first/second image acquisition systems. According to one aspect, the first acquisition system is two-dimensional and includes a first camera having a first optical axis, a first focal plane, a first focal point, and a first depth of field, and a first illumination system that illuminates around the first focal point. According to another aspect, the second image acquisition system is three-dimensional and includes a second camera having a second optical axis, a second focal plane, and a second depth of field, and a second illumination system. A translation plane, substantially orthogonal to the first optical axis, is defined by the first focal point, and an intersection between the second optical axis and the second depth of field.