Invention Grant
- Patent Title: Controlling translocation through nanopores with fluid walls
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Application No.: US16377970Application Date: 2019-04-08
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Publication No.: US10670578B2Publication Date: 2020-06-02
- Inventor: Michael Mayer , Erik Yusko , Jerry Yang
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Harness, Dickey & Pierce, P.L.C.
- Main IPC: G01N33/487
- IPC: G01N33/487 ; G01N27/26 ; B82Y30/00 ; C12Q1/68 ; C12Q1/6869 ; G01N15/12 ; G01N15/00
Abstract:
Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid coatings such as lipid walls. Fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
Public/Granted literature
- US20190234930A1 Controlling Translocation Through Nanopores With Fluid Walls Public/Granted day:2019-08-01
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