A method of orchestrated shuffling of data in a non-uniform memory access device including a plurality of processing nodes that connected by interconnects. The method includes running an application on a plurality of threads executing on the plurality of processing nodes. Data to be shuffled is identified from source threads running on source processing nodes among the processing nodes to target threads executing on target processing nodes among the processing nodes. The method further includes generating a plan for orchestrating the shuffling of the data among the all of the memory devices associated with the threads and for simultaneously transmitting data over different interconnects to a plurality of different target processing nodes from a plurality of different source processing nodes. The data is shuffled among all of the memory devices based on the plan and each processing node is capable of accessing data from first and second local memory devices.