Invention Grant
- Patent Title: Pharmaceutical composition containing 8 OXO-deoxyguanosine or pharmaceutically acceptable salt thereof as active ingredient for treating corneal disease
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Application No.: US16376140Application Date: 2019-04-05
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Publication No.: US10675294B2Publication Date: 2020-06-09
- Inventor: Myung-Hee Chung , Dong Hyun Kim
- Applicant: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION , GIL MEDICAL CENTER
- Applicant Address: KR Seongnam-si, Gyeonggi-Do KR Namdong-Gu, Incheon
- Assignee: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION,GIL MEDICAL CENTER
- Current Assignee: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION,GIL MEDICAL CENTER
- Current Assignee Address: KR Seongnam-si, Gyeonggi-Do KR Namdong-Gu, Incheon
- Agency: Fredrikson & Byron, P.A.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1ffb26aa
- Main IPC: A61K31/708
- IPC: A61K31/708 ; A61P27/02 ; A61K9/00 ; C11D3/00 ; C11D3/28 ; A61K9/08 ; A61K31/522 ; C11D11/00
Abstract:
The present invention relates to a pharmaceutical composition for treating corneal disease containing 8-oxo-deoxyguanosine (8-oxo-2′-deoxyguanosine) or a pharmaceutically acceptable salt thereof as an active ingredient. Specifically, by confirming that a corneal epithelium was restored (regenerated) quicker and the clarity of a cornea improved when it was administered W to a mouse model of corneal disease induced by ethanol, 8-oxo-deoxyguanosine (8-oxo-2′-deoxyguanosine) of the present invention may be useful for the treatment of corneal disease.
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