Invention Grant
- Patent Title: Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
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Application No.: US16703458Application Date: 2019-12-04
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Publication No.: US10675309B2Publication Date: 2020-06-09
- Inventor: Thomas Borody
- Applicant: CRESTOVO HOLDINGS LLC
- Applicant Address: US MA Somerville
- Assignee: Crestovo Holdings LLC
- Current Assignee: Crestovo Holdings LLC
- Current Assignee Address: US MA Somerville
- Agency: Arnold & Porter Kaye Scholer LLP
- Agent David R. Marsh
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2ca744bb
- Main IPC: A61K35/74
- IPC: A61K35/74 ; A61K35/24 ; A61M31/00 ; C12N1/00 ; A61P1/12 ; A61M5/142 ; A61K9/48 ; A61K35/742 ; A61K35/00 ; A61B10/00

Abstract:
In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon; and methods for making and using them. In alternative embodiments, compositions and methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection. In alternative embodiments, the invention provides pharmaceuticals and products (articles) of manufacture for delivering these compositions and formulations to an individual, e.g., a human or an animal. The invention also provides devices for delivering a fecal material to a patient.
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