Invention Grant
- Patent Title: Compositions comprising cupredoxins for treating cancer
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Application No.: US15837683Application Date: 2017-12-11
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Publication No.: US10675326B2Publication Date: 2020-06-09
- Inventor: Brad N. Taylor , Rajeshwari Mehta , Tohru Yamada , Craig Beattie , Tapas Das Gupta
- Applicant: The Board of Trustees of the University of Illinois
- Agency: Benesch, Friedlander, Copla & Aronoff LLP
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61P35/00 ; A61K47/64 ; A61K47/42 ; C07K11/00 ; A61K9/00 ; A61K38/16 ; A61K49/00 ; C07K14/21
Abstract:
The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin.
Public/Granted literature
- US20190046605A1 COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS Public/Granted day:2019-02-14
Information query
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