Invention Grant
- Patent Title: Devices and methods for the detection of molecules using a flow cell
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Application No.: US16229741Application Date: 2018-12-21
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Publication No.: US10675623B2Publication Date: 2020-06-09
- Inventor: Boris Andreyev , Rajinder K. Bhatia , Victor Briones , Phoebe Cao , Jesus Ching , Brian Ciopyk , Adam De La Zerda , Jonathan H. Hong , Helen Huang , Colin Kelly , Adrienne C. Lam , Gregory Loney , Danielle McSheery , Keith E. Moravick , Valeria Revilla , Shaunak Roy , David D. Swenson
- Applicant: Visby Medical, Inc.
- Applicant Address: US CA San Jose
- Assignee: Visby Medical, Inc.
- Current Assignee: Visby Medical, Inc.
- Current Assignee Address: US CA San Jose
- Agency: ReavesColey PLLC
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12Q1/686 ; B01L7/00 ; C12Q1/68

Abstract:
A method includes conveying a detection solution containing a target amplicon into a detection module of a molecular diagnostic test device. The detection module includes a detection surface including a series of capture probes to which a first portion of the target amplicon is bound when the detection solution is conveyed. A first reagent formulated to produce a visible signal indicating a presence of the target amplicon is then conveyed into the detection module. The first reagent is bound to a second portion of the target amplicon when the first reagent is conveyed. A second reagent is conveyed into the detection module. The second reagent includes a precipitating substrate formulated to catalyze the production of the visible signal by producing an insoluble colored product when the second reagent is in contact with the first reagent. The method includes viewing the visible signal via a transparent portion of the detection module.
Public/Granted literature
- US20190151844A1 DEVICES AND METHODS FOR THE DETECTION OF MOLECULES USING A FLOW CELL Public/Granted day:2019-05-23
Information query
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