Invention Grant
- Patent Title: Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis B
-
Application No.: US14423963Application Date: 2013-08-28
-
Publication No.: US10676429B2Publication Date: 2020-06-09
- Inventor: Koen Vandyck , Stefaan Julien Last , Geert Rombouts , Wim Gaston Verschueren , Pierre Jean-Marie Bernard Raboisson
- Applicant: JANSSEN SCIENCES IRELAND UC
- Applicant Address: IE Little Island, County Cork
- Assignee: Janssen Sciences Ireland UC
- Current Assignee: Janssen Sciences Ireland UC
- Current Assignee Address: IE Little Island, County Cork
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7e744f69 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@76c7c94d com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@546d9a1a com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@d749ff4 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@51278634
- International Application: PCT/EP2013/067821 WO 20130828
- International Announcement: WO2014/033170 WO 20140306
- Main IPC: C07D213/42
- IPC: C07D213/42 ; C07D213/81 ; C07D213/82 ; A61K31/44 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; C07C311/37 ; C07C311/14 ; C07C311/16 ; C07C311/20 ; C07C311/51 ; A61K31/18 ; A61K31/337 ; A61K31/341 ; A61K31/351 ; A61K31/4164 ; A61K31/426 ; A61K31/4453 ; A61K31/4468 ; C07D211/96 ; C07D305/08 ; C07D307/22 ; C07D205/04 ; C07D207/273 ; C07D307/60 ; C07D333/38 ; C07D333/48 ; C07D233/90 ; C07D491/107 ; C07D207/14 ; C07D207/36 ; C07D277/56 ; C07D211/28 ; C07D295/13 ; C07D211/56 ; C07D211/76 ; C07D295/26 ; C07D307/68 ; C07D493/08 ; A61K31/34 ; A61K31/397 ; A61K31/495 ; A61K31/5375 ; A61K31/55 ; C07D223/06 ; C07D233/84 ; C07D309/14 ; A61K31/401 ; A61K45/06
Abstract:
Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein B, R1, R2 and R4 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
Public/Granted literature
- US20150266890A1 SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B Public/Granted day:2015-09-24
Information query
IPC分类:
