Invention Grant
- Patent Title: Phenylpyrrolidinone formyl peptide 2 receptor agonists
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Application No.: US16291209Application Date: 2019-03-04
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Publication No.: US10676431B2Publication Date: 2020-06-09
- Inventor: Pravin Sudhakar Shirude , Vishweshwaraiah Baligar , Balaji Seshadri , Amit Kumar Chattopadhyay , Nicholas R. Wurtz , Ellen K. Kick
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- Main IPC: C07D207/14
- IPC: C07D207/14 ; C07D403/10 ; C07D401/10 ; C07D401/12 ; C07D413/10 ; C07D409/12 ; A61P9/04 ; C07D403/12 ; C07F9/6558 ; C07D405/10 ; C07F9/572 ; A61P9/00 ; C07D417/10 ; C07D413/14 ; A61P9/10
Abstract:
The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
Public/Granted literature
- US20190270704A1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS Public/Granted day:2019-09-05
Information query
