Invention Grant
![Method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile](/docs/US/2020-06-09/US10676443B2/abs.jpg.600x600.jpg)
- Patent Title: Method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile
-
Application No.: US16394811Application Date: 2019-04-25
-
Publication No.: US10676443B2Publication Date: 2020-06-09
- Inventor: Heiko Schirmer , Philipp Rubenbauer , Birgit Keil , Britta Olenik
- Applicant: pH Pharma Co., Ltd.
- Applicant Address: KR Seoul
- Assignee: pH Pharma Co., Ltd.
- Current Assignee: pH Pharma Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Viksnins Harris Padys Malen LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3df92868
- Main IPC: C07D239/22
- IPC: C07D239/22 ; C07C315/00
![Method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile](/abs-image/US/2020/06/09/US10676443B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to a new and improved method for preparation of (4S)-4-[4-cyano-2-(methyl sulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I), as well as the preparation and use of the crystal form (A) of (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I).
Public/Granted literature
Information query
