Invention Grant
- Patent Title: Crystalline salts and polymorphs of a P2X3 antagonist
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Application No.: US16468992Application Date: 2017-12-15
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Publication No.: US10676444B2Publication Date: 2020-06-09
- Inventor: Prabha Ibrahim , Ronald Charles Hawley , Anthony P. Ford , Steven A. Smith
- Applicant: Afferent Pharmaceuticals, Inc.
- Applicant Address: US CA San Mateo
- Assignee: Afferent Pharmaceuticals, Inc.
- Current Assignee: Afferent Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Mateo
- Agent Yong Zhao; Anna L. Cocuzzo
- International Application: PCT/US2017/066562 WO 20171215
- International Announcement: WO2018/118668 WO 20180628
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61K9/20 ; A61K31/191
Abstract:
Provided are novel salts and polymorphs of 5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-benzenesulfonamide, which are potentially useful for modulating a condition mediated by a P2X3 or P2X2/3 receptor. Also provided are pharmaceutical formulations and methods of administration and dosing of these salts and polymorphs to subjects in need thereof.
Public/Granted literature
- US20190315698A1 CRYSTALLINE SALTS AND POLYMORPHS OF A P2X3 ANTAGONIST Public/Granted day:2019-10-17
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