Invention Grant
- Patent Title: Compound for the prophylaxis or treatment of organ damage
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Application No.: US15576290Application Date: 2016-05-12
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Publication No.: US10676452B2Publication Date: 2020-06-09
- Inventor: Adrianus Cornelis Van Der Graaf , Robert Henk Henning , Leo Edwin Deelman , Gerrit Jan Willem Euverink
- Applicant: Sulfateq B.V.
- Applicant Address: NL Groningen
- Assignee: Sulfateq B.V.
- Current Assignee: Sulfateq B.V.
- Current Assignee Address: NL Groningen
- Agency: Hoyng Rokh Monegier LLP
- Agent David P. Owen
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5d6fde2c
- International Application: PCT/EP2016/060731 WO 20160512
- International Announcement: WO2016/188766 WO 20161201
- Main IPC: C07D311/72
- IPC: C07D311/72 ; A61K31/353 ; A61P13/12 ; C07D405/06
Abstract:
The present invention relates to compounds for prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially to compounds for prophylaxis or treatment of diabetic kidney damage. Specifically, the present invention relates to 6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone or N,6-dihydroxy-2,5,7,8-tetramethylchroman-2-carboxamide or a pharmaceutically acceptable salt or base thereof for use in the prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially diabetic kidney organ damage.
Public/Granted literature
- US20180170892A1 COMPOUND FOR THE PROPHYLAXIS OR TREATMENT OF ORGAN DAGAMAGE Public/Granted day:2018-06-21
Information query
