Invention Grant
- Patent Title: Anti-coagulation factor XI antibodies
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Application No.: US15619620Application Date: 2017-06-12
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Publication No.: US10676536B2Publication Date: 2020-06-09
- Inventor: Zhu Chen , Kenneth Ellsworth , James Milligan , Elizabeth Oldham , Dietmar Seiffert , Bianka Prinz
- Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
- Applicant Address: US NJ Rahway US NJ Lebanon
- Assignee: Merck Sharp & Dohme Corp.,ADIMAB, LLC
- Current Assignee: Merck Sharp & Dohme Corp.,ADIMAB, LLC
- Current Assignee Address: US NJ Rahway US NJ Lebanon
- Agent John David Reilly; Anna L. Cocuzzo
- Main IPC: C07K16/36
- IPC: C07K16/36 ; A61K39/395 ; A61K39/00
Abstract:
Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
Public/Granted literature
- US20170355780A1 ANTI-COAGULATION FACTOR XI ANTIBODIES Public/Granted day:2017-12-14
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