Invention Grant
- Patent Title: Assays and methods for detecting mycobacterial infections
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Application No.: US16083807Application Date: 2017-03-10
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Publication No.: US10677797B2Publication Date: 2020-06-09
- Inventor: Tsungda Hsu
- Applicant: S&R Pharmaceuticals, LLC
- Applicant Address: US MA Lenox
- Assignee: S&R PHARMACEUTICALS, LLC
- Current Assignee: S&R PHARMACEUTICALS, LLC
- Current Assignee Address: US MA Lenox
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- International Application: PCT/US2017/021873 WO 20170310
- International Announcement: WO2017/156436 WO 20170914
- Main IPC: A61K39/04
- IPC: A61K39/04 ; C12Q1/00 ; G01N33/53 ; G01N33/569 ; G01N33/558 ; C12Q1/689
Abstract:
Provided herein is an assay for detecting a rough-type mycobacterium and a smooth-type mycobacterium in a sample, wherein the mycobacterium is Mycobacterium tuberculosis or Mycobacterium bovis. The assay comprises a first molecule that selectively binds to the rough-type mycobacterium or binds to a molecule preferentially secreted by the rough-type mycobacterium and a second molecule that selectively binds to the smooth-type mycobacterium or binds to a molecule preferentially secreted by the smooth-type mycobacterium. The first molecule and the second molecule are independently detectable. Also provided herein are corresponding methods for detecting a rough-type mycobacterium and a smooth-type mycobacterium in a sample and assays and methods for detecting tuberculosis infection in a sample.
Public/Granted literature
- US20190137492A1 Assays And Methods For Detecting Mycobacterial Infections Public/Granted day:2019-05-09
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