An information handling system may include a processor, a memory, modules including one or more information handling resources and having a corresponding airflow impedance associated therewith, and a cooling system that includes a controller and of air movers. The controller may be configured to, in response to a determination that a first module of the plurality of modules has a first airflow impedance higher than an upper threshold impedance and that a second module of the plurality of modules has a second airflow impedance lower than a lower threshold impedance: determine a scaling factor based on the first and second airflow impedances, scaling factor being usable by the controller to adjust an amount of airflow provided by the plurality of air movers; and control the plurality of air movers in an open-loop fashion according to the scaling factor.