Aspects provide multi-tier data synchronization based on a concurrent linked monitor list. A computer processor associates each of different data regions of a packed data object with different mutual exclusion monitor nodes of a linked list, the data regions defined by a data offset location within memory data and a length of the data region from the offset. In response to determining that a first data region of the packed data object is on-heap memory, the processor associates the first data region with a container representative of the linked list sorted in ascending order of the respective offset values, and a hash code of the container; and in response to determining that a second data region of the packed data object is off-heap memory, stores container information for the second data region in the linked list and resorts the linked-list nodes of container information in ascending order of offset values.