Disclosed are various examples for remote virtual private network (VPN) configuration using dynamically generated configuration profiles. A computing environment having a management service can determine variable names for inclusion in configuration profiles that are capable of configuring VPN settings on various managed device operating systems. The computing environment can dynamically generate configuration profiles using the appropriate variable names such that a client device having a particular operating system installed thereon is capable of interpreting the value and the variable name to configure the VPN setting.