Redundancy in over-voltage fault protection may be provided by controlling switches already present in a power path of a port for an information handling system. An external device coupled to a port may be decoupled from the system when an over-voltage condition is detected at another port of the information handling system. To decouple an external device upon detection of an over-voltage condition, a switch coupled to the port and the external device is turned off. A battery may also be decoupled from a port upon detection of an over-voltage condition at another port.