Methods, apparatus, systems and articles of manufacture to monitor the personal safety of a user of a portable electronic device are disclosed. Example safety managers disclosed herein include processor circuitry to determine whether data collected from a remote electronic device corresponds to a first usage context profile associated with the remote electronic device, obtain a threshold alert level corresponding to the first usage context profile when the collected data corresponds to the first usage context profile, the threshold alert level to indicate a degree of danger to which a user is exposed, adjust the threshold alert level based on information obtained from a data source different from the remote electronic device, monitor usage attributes reported by the remote electronic device to determine whether the threshold alert level has been satisfied, and actuate a safety alert associated with the remote electronic device when the threshold alert level has been satisfied.