An asset location and management system, the system including multiple reader nodes, each reader node having a Bluetooth Low Energy (BLE) radio in communication with a plurality of peripheral devices, a local service module and a communications manager in communication with a cloud server. The system further including the cloud server having a communication module, a process flow library to describe how peripheral devices are expected to move through a facility, a rules library describing trigger events associated with one or more peripheral device and identifying a corresponding action for each trigger event, and a real-time compute engine to generate a sequence of events based on the data from the peripheral devices and the process flow library.