- Patent Title: Block copolymers and self-assembling nanoparticles formed therefrom
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Application No.: US16451489Application Date: 2019-06-25
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Publication No.: US10682313B2Publication Date: 2020-06-16
- Inventor: Dylan Boday , Willy Chin , Mareva B. Fevre , Jeannette Garcia , James L. Hedrick , Eunice Leong , Nathaniel H. Park , Rudy J. Wojtecki , Yi Yan Yang
- Applicant: International Business Machines Corporation , Institute of Bioengineering and Nanotechnology, Biomedical Sciences Institute
- Applicant Address: US NY Armonk SG Matrix
- Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION,INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY, BIOMEDICAL SCIENCES INSTITUTE
- Current Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION,INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY, BIOMEDICAL SCIENCES INSTITUTE
- Current Assignee Address: US NY Armonk SG Matrix
- Agency: Amin, Turocy & Watson, LLP
- Main IPC: A61K31/704
- IPC: A61K31/704 ; A61K47/60 ; A61K47/69 ; A61K9/107 ; C08G64/02 ; C08G81/00 ; C08G64/18 ; C08G83/00 ; A61K31/351 ; A61K31/12
Abstract:
The subject matter of this invention relates to block copolymers (BCPs) and, more particularly, to block copolymers capable of self-assembly into nanoparticles for the delivery of hydrophobic cargos. The BCPs include a hydrophobic block that contains a thioether functional group that is susceptible to oxidation, transforming the solubility of the block from hydrophobic to hydrophilic, thereby releasing the hydrophobic cargo of the nanoparticle.
Public/Granted literature
- US20190307684A1 BLOCK COPOLYMERS AND SELF-ASSEMBLING NANOPARTICLES FORMED THEREFROM Public/Granted day:2019-10-10
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