Invention Grant
- Patent Title: PDE4 modulators for treating and preventing immune reconstitution inflammatory syndrome (IRIS)
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Application No.: US15769713Application Date: 2016-10-20
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Publication No.: US10682336B2Publication Date: 2020-06-16
- Inventor: Vikram Khetani , Jerome Zeldis
- Applicant: Celgene Corporation
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2016/057820 WO 20161020
- International Announcement: WO2017/070291 WO 20170427
- Main IPC: A61P31/22
- IPC: A61P31/22 ; A61P31/14 ; A61P31/06 ; A61P31/10 ; C07K14/81 ; A61K31/4035 ; A61K45/06
Abstract:
Methods of treating immune reconstitution inflammatory syndrome (IRIS) in immunodeficient patients, including HIV patients, using PDE4 modulators are described.
Public/Granted literature
- US20180318257A1 PDE4 MODULATORS FOR TREATING AND PREVENTING IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS) Public/Granted day:2018-11-08
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