Invention Grant
- Patent Title: Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
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Application No.: US15576824Application Date: 2017-11-07
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Publication No.: US10682346B2Publication Date: 2020-06-16
- Inventor: Vered Behar , Oren Menahem Becker , Reut Yosef Hamo , Eyal Dor-On
- Applicant: Vidac Pharma Ltd.
- Applicant Address: IL Jerusalem
- Assignee: VIDAC PHARMA LTD.
- Current Assignee: VIDAC PHARMA LTD.
- Current Assignee Address: IL Jerusalem
- Agency: Pearl Cohen Zedek Latzer Baratz, LLP
- Agent Mark S. Cohen
- International Application: PCT/IL2017/051213 WO 20171107
- International Announcement: WO2018/083704 WO 20180511
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/496 ; A61P35/00 ; A61P37/04 ; A61K9/00 ; A61K9/06 ; A61K31/506 ; A61K35/17 ; A61K39/395 ; A61K45/06
Abstract:
The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
Public/Granted literature
- US20180303819A1 USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES Public/Granted day:2018-10-25
Information query
