Invention Grant
- Patent Title: Compound having mutant IDH inhibitory activity, preparation method and use thereof
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Application No.: US16087556Application Date: 2017-03-21
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Publication No.: US10682352B2Publication Date: 2020-06-16
- Inventor: Lei Jiang , Meiyu Geng , Qiangang Zheng , Min Huang , Huixin Wan , Shuai Tang , Xianlei Fu , Xiaojing Lan , Jianhua Cao , Feifei Liu , Jian Ding
- Applicant: SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. , SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- Applicant Address: CN Shanghai CN Shanghai
- Assignee: SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.,SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- Current Assignee: SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.,SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- Current Assignee Address: CN Shanghai CN Shanghai
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@4dda2d24
- International Application: PCT/CN2017/077467 WO 20170321
- International Announcement: WO2017/162133 WO 20170928
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61P35/00 ; A61P35/02 ; C07D403/04 ; C07D403/14 ; C07D413/04 ; C07D413/14 ; C07D401/14 ; C07D405/14
Abstract:
Provided in the present invention are a compound having the effects of preventing and treating diseases related to IDH mutation, and a preparation method and use thereof. In particular, provided in the present invention are the compound as shown in formula (I), a stereoisomer, a racemic body or a pharmaceutically acceptable salt thereof, and the use thereof in preparing drugs for preventing and treating diseases related to IDH mutation
Public/Granted literature
- US20190111056A1 COMPOUND HAVING MUTANT IDH INHIBITORY ACTIVITY, PREPARATION METHOD AND USE THEREOF Public/Granted day:2019-04-18
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