Invention Grant
- Patent Title: NKP30 receptor targeted therapeutics
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Application No.: US15830605Application Date: 2017-12-04
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Publication No.: US10682378B2Publication Date: 2020-06-16
- Inventor: Tong Zhang , Charles L. Sentman
- Applicant: THE TRUSTEES OF DARTMOUTH COLLEGE
- Applicant Address: US NH Hanover
- Assignee: THE TRUSTEES OF DARTMOUTH COLLEGE
- Current Assignee: THE TRUSTEES OF DARTMOUTH COLLEGE
- Current Assignee Address: US NH Hanover
- Agency: Baker, Donelson, Bearman, Caldwell & Berkowitz, PC
- Agent Robin L. Teskin
- Main IPC: A61K35/17
- IPC: A61K35/17 ; C07K14/705 ; C12N5/0783 ; A61K38/00

Abstract:
The invention is directed to T cells and other cells that express chimeric NK-p30 receptors (“chimeric NKp30 T cells”), methods of making and using chimeric NKp30 T cells, and methods of using these chimeric NKp30 T cells, isolated populations thereof, and compositions comprising the same. In another aspect, said chimeric NKp30 T cells are further designed to express a functional non-TCR receptor. The disclosure also pertains to methods of making said chimeric NKp30 T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said chimeric NKp30 T cells, populations thereof, or compositions comprising the same.
Public/Granted literature
- US20180147240A1 NKP30 RECEPTOR TARGETED THERAPEUTICS Public/Granted day:2018-05-31
Information query
IPC分类: