Invention Grant
- Patent Title: TLR7 agonist trifluoroacetate salt and crystalline form B thereof, preparation methods and uses
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Application No.: US16075303Application Date: 2017-02-04
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Publication No.: US10683296B2Publication Date: 2020-06-16
- Inventor: Zhaozhong Ding , Fei Sun , Yinghu Hu , Yilong Zhou , Zheng Wang , Rui Zhao , Ling Yang
- Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- Applicant Address: CN Jiangsu, Lianyungang
- Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- Current Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- Current Assignee Address: CN Jiangsu, Lianyungang
- Agency: Foley & Lardner LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@661ac659
- International Application: PCT/CN2017/072894 WO 20170204
- International Announcement: WO2017/133687 WO 20170810
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61P31/14 ; A61P31/20 ; A61K31/519 ; A61P31/12
Abstract:
The present invention relates to a trifluoroacetate salt of a TLR7 agonist 2-butoxy-7-(4-(pyrrolidin-1-ylmethyl)benzyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine (formula I), crystalline form B of the trifluoroacetate salt, methods for preparing the trifluoroacetate salt and crystalline form B, and uses of the trifluoroacetate salt and crystalline form B.
Public/Granted literature
- US20190031666A1 TLR7 AGONIST TRIFLUOROACETATE SALT AND CRYSTALLINE FORM B THEREOF, PREPARATION METHODS AND USES Public/Granted day:2019-01-31
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