Invention Grant
- Patent Title: Compositions and methods for modulating TTR expression
-
Application No.: US15687306Application Date: 2017-08-25
-
Publication No.: US10683499B2Publication Date: 2020-06-16
- Inventor: Thazha P. Prakash , Punit P. Seth , Eric E. Swayze
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe, Martens, Olson & Bear LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113 ; A61K47/54 ; C12N15/11 ; A61K31/7088 ; A61K31/713

Abstract:
Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
Public/Granted literature
- US20180044676A1 COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION Public/Granted day:2018-02-15
Information query