Invention Grant
- Patent Title: Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases
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Application No.: US16223362Application Date: 2018-12-18
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Publication No.: US10683501B2Publication Date: 2020-06-16
- Inventor: Tracy Zimmermann , Amy Chan , Vasant R. Jadhav , Martin A. Maier , Kallanthottathil G. Rajeev
- Applicant: Alnylam Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Deborah L. Nagle
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/113
Abstract:
The present invention provides iRNA agents, e.g., double stranded iRNA agents, that target the transthyretin (TTR) gene and methods of using such iRNA agents for treating or preventing TTR-associated diseases.
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