A multi-stage electric centrifugal compressor including an electric motor free from risk of breakdown of an operation control part due to heat generated by low-pressure stage and high-pressure stage compressors. Includes an electric motor; a pair of centrifugal compressors comprising a low-pressure stage compressor and a high-pressure stage compressor connected in series; a heat-shielding plate configured to shield heat generated by the low-pressure stage compressor; and a bending portion disposed in middle of the heat-shielding plate, and extending along a rotational shaft of the electric motor so as to surround an outer periphery of the rotational shaft. An inner surface of the bending portion faces the rotational shaft via a clearance part, and the bending portion functions as a shaft sealing portion which prevents leakage of intake air from the low-pressure stage compressor.