An experiment manager is discussed for the design and execution of numerical experiments in composite simulation models, such as those created using the Smarter Planet Platform for Analysis Simulation of Health (Splash). The experiment manager independently elicits experiment-related information from each contributor of a component model, and uses this information to subsequently assist the creator of a composite model in selecting experimental factors, creating experimental designs based on these factors, and executing the experiments. This functionality permits cross-disciplinary modeling, simulation, sensitivity analysis and optimization in the setting of complex systems.