Spatial multiplexing and transmit diversity can improve the capacity of a wireless communication system. The system and method adapts communication schemes for communication systems with multiple antennas utilizing at least two transmission modes. The at least two transmission modes can, but are not necessarily, used for uplink communications. The two transmission modes may be chosen from the group consisting of a single antenna mode, a diversity mode a spatial multiplexed mode and a mixed diversity and spatial multiplexed mode. The at least two transmission modes may involve adaptation among multiple transmitters. At least one receiver may indicate a transmission mode to be used by a transmitter for a subsequent transmission. A transmitter may determine a transmission mode to be used for a subsequent transmission. The transmission mode can be based on channel sounding.