A signal transmission structure for speaker includes a base having two outgoing lead grooves provided on the same side thereof; a magnet member arranged on the base; a voice coil movably disposed over the magnet member; two tinsel leads respectively having an end connected to two opposite sides of the voice coil and another end set in the two outgoing lead grooves; and a signal connection board disposed in the base with two tinsel lead welding pads and two hook-up wire welding pads provided on a top and a bottom surface thereof, respectively. The tinsel lead welding pads are located between the voice coil and the outgoing lead grooves, allowing the two tinsel leads to be separately welded thereto. With the above signal transmission structure for speaker, welding of tinsel leads and hook-up wires thereto can be conveniently performed to reduce labor and time costs.