Invention Grant
- Patent Title: Substituted indoline derivatives as dengue viral replication inhibitors
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Application No.: US16088090Application Date: 2017-03-31
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Publication No.: US10689340B2Publication Date: 2020-06-23
- Inventor: Bart Rudolf Romanie Kesteleyn , Pierre Jean-Marie Bernard Raboisson , Jean-François Bonfanti , Dorothée Alice Marie-Eve Bardiot , Arnaud Didier M Marchand
- Applicant: Janssen Pharmaceuticals, Inc. , Katholieke Universiteit Leuven
- Applicant Address: US NJ Titusville BE Leuven
- Assignee: Janssen Pharmaceuticals, Inc.,Katholieke Universiteit Leuven
- Current Assignee: Janssen Pharmaceuticals, Inc.,Katholieke Universiteit Leuven
- Current Assignee Address: US NJ Titusville BE Leuven
- Agency: Amster, Rothstein & Ebenstein LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6da96675
- International Application: PCT/EP2017/057661 WO 20170331
- International Announcement: WO2017/167951 WO 20171005
- Main IPC: C07D209/08
- IPC: C07D209/08 ; C07D209/26 ; A61P31/14

Abstract:
The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
Public/Granted literature
- US20190112266A1 Substituted indoline derivatives as dengue viral replication inhibitors Public/Granted day:2019-04-18
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