- Patent Title: Bicyclic aza compounds as muscarinic M1 receptor and/or M4 receptor
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Application No.: US16459179Application Date: 2019-07-01
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Publication No.: US10689368B2Publication Date: 2020-06-23
- Inventor: Giles Albert Brown , Julie Elaine Cansfield , Miles Stuart Congreve , Michael Alistair O'Brien , Mark Pickworth , Mark David Rackham , Benjamin Gerald Tehan , Barry John Teobald
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Cambridge
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Cambridge
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@f07f0d5 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@18352e5e
- Main IPC: A61K31/4545
- IPC: A61K31/4545 ; A61K31/454 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D401/04 ; C07D409/14 ; C07D417/14 ; C07D471/04 ; C07D491/107
Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1, or a salt thereof, wherein Q, R1, R2, R3 and R4 are as defined herein.
Public/Granted literature
- US20190337925A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR Public/Granted day:2019-11-07
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