Invention Grant
- Patent Title: Anti-cancer compounds targeting ral GTPases and methods of using the same
-
Application No.: US15142011Application Date: 2016-04-29
-
Publication No.: US10689392B2Publication Date: 2020-06-23
- Inventor: Dan Theodorescu , Michael Fitzpatrick Wempe , David Ross , Samy Meroueh , Martin A. Schwartz , Phillip Reigan
- Applicant: The Regents of the University of Colorado, a body corporate
- Applicant Address: US CO Denver US IN Indianapolis US VA Charlottesville
- Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE,INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION,UNIVERSITY OF VIRGINIA PATENT FOUNDATION
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE,INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION,UNIVERSITY OF VIRGINIA PATENT FOUNDATION
- Current Assignee Address: US CO Denver US IN Indianapolis US VA Charlottesville
- Agency: Greenberg Traurig, LLP
- Agent Jonathan D. Ball; Evelyn M. Kwon
- Main IPC: C07D491/052
- IPC: C07D491/052 ; A61K31/4162 ; A61K31/351 ; A61K31/437 ; A61K31/505 ; A61K31/5513 ; A61K45/06
Abstract:
The invention provides methods of inhibiting the growth or metastasis of a cancer in a mammal by inhibiting a Ral GTPase in the mammal. The invention also provides small molecule inhibitors of Ral GTPases useful in the methods of the invention and pharmaceutical compositions containing the therapeutically effective compounds of the invention, and methods of using the same.
Public/Granted literature
- US20160280715A1 ANTI-CANCER COMPOUNDS TARGETING RAL GTPASES AND METHODS OF USING THE SAME Public/Granted day:2016-09-29
Information query
