Invention Grant
- Patent Title: ULK1 inhibitors and methods using same
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Application No.: US16269468Application Date: 2019-02-06
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Publication No.: US10689397B2Publication Date: 2020-06-23
- Inventor: Reuben J. Shaw , Daniel F. Egan , Nicholas Cosford , Benjamin Turk , Mitchell Vamos , Dhanya Raveendra Panickar , Matthew Chun , Douglas Sheffler
- Applicant: SALK INSTITUTE FOR BIOLOGICAL STUDIES , SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE , YALE UNIVERSITY
- Applicant Address: US CA La Jolla US CA La Jolla US CT New Haven
- Assignee: SALK INSTITUTE FOR BIOLOGICAL STUDIES,SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE,YALE UNIVERSITY
- Current Assignee: SALK INSTITUTE FOR BIOLOGICAL STUDIES,SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE,YALE UNIVERSITY
- Current Assignee Address: US CA La Jolla US CA La Jolla US CT New Haven
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/5383 ; A61K31/506 ; C07D239/42 ; C07D417/04 ; C07D403/12 ; C07D401/14 ; C07D405/12 ; C07D401/12 ; A61K45/06 ; C12Q1/48 ; C07K7/08 ; C07D498/04 ; C07D405/14 ; C07D413/14 ; C07D239/48 ; C07D239/557 ; C07D471/04 ; A61K31/5377 ; C07D239/34 ; C07D239/47 ; C07D417/12 ; C07D417/14
Abstract:
In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
Public/Granted literature
- US20190152989A1 NOVEL ULK1 INHIBITORS AND METHODS USING SAME Public/Granted day:2019-05-23
Information query
