Invention Grant
- Patent Title: Multimeric death domain-containing receptor-5 (DR5) antibodies and uses thereof
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Application No.: US15544873Application Date: 2016-01-20
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Publication No.: US10689449B2Publication Date: 2020-06-23
- Inventor: Beatrice Tien-Yi Wang , Max A. Schwarzer , Bruce Alan Keyt , Ramesh Baliga
- Applicant: IGM Biosciences, Inc.
- Applicant Address: US CA Mountain View
- Assignee: IGM Biosciences, Inc.
- Current Assignee: IGM Biosciences, Inc.
- Current Assignee Address: US CA Mountain View
- International Application: PCT/US2016/014153 WO 20160120
- International Announcement: WO2016/118641 WO 20160728
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; C07K14/705
Abstract:
This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.
Public/Granted literature
- US20180009897A1 TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY RECEPTOR BINDING MOLECULES AND USES THEREOF Public/Granted day:2018-01-11
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