A power switch circuit including first and second transistors, and a control circuit is provided. A first end of the first transistor serves as an input terminal of the power switch circuit. A second end of the first transistor is coupled to a node. A control end of the first transistor receives a first control voltage. A first end of the second transistor serves as an output terminal of the power switch circuit. A second end of the second transistor is coupled to the node. A control end of the second transistor receives a second control voltage. The control circuit detects a voltage of the node to determine a type of series connection between the first and second transistors, and generates the first and second control voltages to control a turned-on state of another of the first and second transistors after turning on one of the first and second transistors.