Invention Grant
- Patent Title: Solid preparation containing alkyl cellulose and method for producing the same
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Application No.: US15450151Application Date: 2017-03-06
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Publication No.: US10696751B2Publication Date: 2020-06-30
- Inventor: Takuya Yokosawa , Naosuke Maruyama , Akira Kitamura
- Applicant: Shin-Etsu Chemical Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: SHIN-ETSU CHEMICAL CO., LTD.
- Current Assignee: SHIN-ETSU CHEMICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Rimon, P.C.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@74970051
- Main IPC: C08B11/02
- IPC: C08B11/02 ; C11D3/22 ; A61K47/38 ; C11D17/00 ; A61K9/20 ; A61K31/167

Abstract:
Provided are a solid preparation comprising an alkyl cellulose which provides excellent moldability and disintegrability even in a small amount of the alkyl cellulose, and a production method therefor. Specifically, provided are a solid preparation having an alkyl cellulose having a specific surface area by BET method of 0.5 to 10.0 m2/g and a dissolution start temperature of 5 to 27° C.; and a method for producing a solid preparation having the steps of: mixing a cellulose pulp and a first alkali metal hydroxide solution with stirring to obtain alkali cellulose, reacting the alkali cellulose with an alkylating agent to obtain a first reaction mixture, mixing the first reaction mixture and a second alkali metal hydroxide solution with stirring and without further addition of any alkylating agent to obtain a second reaction mixture, and pulverizing an alkyl cellulose isolated from the second reaction mixture to obtain an alkyl cellulose.
Public/Granted literature
- US20170260295A1 SOLID PREPARATION CONTAINING ALKYL CELLULOSE AND METHOD FOR PRODUCING THE SAME Public/Granted day:2017-09-14
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