Invention Grant
- Patent Title: MrgprX2/MrgprB2 expressing cell based assay to detect pseudo-allergic drug reactions and to identify blockers to prevent the adverse reactions
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Application No.: US15329383Application Date: 2015-07-31
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Publication No.: US10696971B2Publication Date: 2020-06-30
- Inventor: Xinzhong Dong , Benjamin McNeil
- Applicant: The Johns Hopkins University
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Peter F. Corless
- International Application: PCT/US2015/043116 WO 20150731
- International Announcement: WO2016/019246 WO 20160204
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C07K14/705 ; C07K14/72 ; A61K31/7105 ; G01N33/50 ; A61K31/713 ; A01K67/027 ; A61K45/06
Abstract:
The present invention relates to cells and methods for detecting compounds that induce a pseudo-allergic-type reaction and methods for reducing the severity of a pseudo-allergic-type reaction.
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