Invention Grant
- Patent Title: Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists
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Application No.: US15899629Application Date: 2018-02-20
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Publication No.: US10697025B2Publication Date: 2020-06-30
- Inventor: Mei W. Chen , Cindy Collins , Matthew L. Eaton , Matthew G. Guenther , Nan Ke , Jeremy Lopez , Michael R. McKeown , David A. Orlando
- Applicant: Syros Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Syros Pharmaceuticals, Inc.
- Current Assignee: Syros Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; Janet M. Tse
- Main IPC: A61K31/165
- IPC: A61K31/165 ; A61K31/167 ; C12Q1/6886 ; A61K31/166 ; A61K31/196 ; A61K31/192 ; A61K31/195
Abstract:
The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
Public/Granted literature
- US20180187271A1 METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS Public/Granted day:2018-07-05
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