Invention Grant
- Patent Title: CXCR4 and ROBO1 expression as markers for autoimmune diabetes
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Application No.: US14950202Application Date: 2015-11-24
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Publication No.: US10697960B2Publication Date: 2020-06-30
- Inventor: Christopher Kevil , Robert McVie , John Glawe
- Applicant: Christopher Kevil , Robert McVie , John Glawe
- Applicant Address: US LA Shreveport
- Assignee: BOARD OF SUPERVISORS OR LOUISANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
- Current Assignee: BOARD OF SUPERVISORS OR LOUISANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
- Current Assignee Address: US LA Shreveport
- Agency: Davis & Bujold PLLC
- Agent Charles G. Holoubek
- Main IPC: G01N33/564
- IPC: G01N33/564 ; C12Q1/68 ; G01N33/566 ; A61K38/19 ; G01N33/50 ; C12Q1/6883 ; A61K49/00
Abstract:
CXCR4 and ROBO-1 are biomarkers associated with type 1 diabetes. Expression of CXCR4 and ROBO-1 in peripheral CD3 T cells is substantially higher in patients with autoimmune diabetes (type 1 diabetes) than in non-diabetic patients. Therapies are disclosed for reducing the progression of type 1 diabetes, and to reduce the risk of developing type 1 diabetes in patients who are at risk of developing type 1 diabetes.
Public/Granted literature
- US20160146807A1 CXCR4 AND ROBO1 EXPRESSION AS MARKERS FOR AUTOIMMUNE DIABETES Public/Granted day:2016-05-26
Information query
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