A detachable computer mouse includes a mouse body and a detachable input module. The mouse body is provided with a plurality of first magnetic members, a pogo-pin assembly, a first snap-fit member and a second snap-fit member. The detachable input module is provided with a plurality of second magnetic members, a metal pad assembly, a first hook and a second hook, and a plurality of function buttons. The first magnetic members are correspondingly and magnetically adhered with the second magnetic members, the pogo-pin assembly is correspondingly in direct contact with the metal pad assembly, and the first snap-fit member and the second snap-fit member are respectively elastically snap-fitted to the first hook and the second hook when the detachable input module is coupled to the mouse body.