Aspects of the disclosure relate to preventing unauthorized access to secure enterprise information systems using a multi-intercept system. A computing platform may monitor, in a passive operational state, first communications across a plurality of computer systems in a protected zone of a computing environment using a plurality of communication monitoring nodes deployed in the protected zone of the computing environment. Subsequently, the computing platform may generate current data movement pattern data. If the computing platform determines that the current data movement pattern data is invalid, the computing platform may switch from the passive operational state to an active operational state and may generate and send an active intercept response command. The active intercept response command may redirect one or more requests from a malicious system into a virtual tunnel configured to route second communications from the malicious system out of the protected zone of the computing environment.